Suppressed Fluctuation in The GABAergic Signaling: Mathematical Modelling of The Neurotransmitter
DOI:
https://doi.org/10.14331/ijfps.2015.330093Keywords:
GABA, receptors, Signal, Magnetic Resonance ImagingAbstract
The chemistry of the gamma aminobutyric acid (GABA) had been established. However, the explanation on the interplay
between GABA receptors antagonize fundamental concept of the GABAergic Signaling . For example, glutamate spillover
from excitatory afferent terminals leads to the modulation of GABAergic signals. However, this result is true with respect to
GABAB receptors only. The physics of its interplay between the GABA receptors was theoretically investigated using the
magnetic resonance imaging (MRI) because the proton gradient controls the intermediate energy storage for heat production
and flagellar rotation. The MRI investigation of the GABAergic Signaling is not a new concept in medicine. Molecular
potential in the receptors increases the peak radiofrequency (RF) field (B1) amplitude and the holding potential of the GABA
receptors. The suppressed fluctuation of the GABAergic Signaling was noticed where the receptors are all actively involved
in the GABAergic network. Hence, a dual technique was suggested to detect the suppressed GABAergic state in the human
body.
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